Figure 8.
Effects of ETA and ETB receptor antagonists on the ACh-induced relaxations of penile arteries of LZR and OZR. Average effects of (A, B) the ETA receptor antagonist BQ123 (1 μM), (C, D) the ETB receptor antagonist BQ788 (0.1 μM) or (E,F) combined blockade of ETA receptors (BQ123, 1 μM) and ETB receptor (BQ788, 0.1 μM) on the relaxant responses elicited by ACh in penile arteries from LZR (A, C, E) and OZR (B, D, F). Results are means ± SEM of 6–8 arteries. *P < 0.05, **P < 0.01 versus control; Student's t-test for paired observations.