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Effect of treatment after onset of uveitis with melatonin on PGE2 and PGF2α levels in the aqueous humour from eyes injected with vehicle or LPS. At 36 h post-injection, LPS induced a significant increase in PG levels, whereas both treatments with melatonin (i.e. Mel 12 h and Mel 24 h) significantly decreased PGE2 and PGF2α content. Data are mean ± SEM (n = 12 eyes per group). **P < 0.01 versus vehicle-injected eyes; †P < 0.01 versus LPS-injected eyes, by Tukey's test.
