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. 2014 Dec 8;8(Suppl 4):S9. doi: 10.1186/1752-0509-8-S4-S9

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Copyright © 2014 Lai et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Performance evaluation and comparison using TF-based performance indices. (a) Index 1 is based on PPI partners overlap of a predicted cooperative TF pair (PCTFP); (b) Index 2 is based on the shortest path length of a PCTFP in the PPI network; (c) Index 3 is based on the functional similarity of a PCTFP; (d) Index 4 based on the overlap between a set of PCTFPs and a benchmarked set of 27 known cooperative TF pairs. The blue bar indicates the algorithm which outperforms the others using that performance index.