Table 1.
Clinical, electrocardiographic, echocardiographic and Holter findings of 72 patients with Chagas disease
| Characteristics | N (%) |
|---|---|
| Clinical characteristics | |
| Age in years (mean ± standard deviation) | 59.3 ± 10.6 |
| Male gender | 35 (48.6) |
| Dyslipidemia | 27 (37.5) |
| Syncope | 43 (59.7) |
| Smoking | 5 (6.9) |
| Stroke or TIA | 7 (9.7) |
| Systemic arterial hypertension | 55 (76.4) |
| Diabetes mellitus | 10 (13.9) |
| Implantable cardioverter | 2 (2.8) |
| Pacemaker | 2 (2.8) |
| Functional class | |
| I | 37 (51.4) |
| II | 30 (41.7) |
| III | 5 (6.9) |
| IV | 0 (0.0) |
| Concomitant medications | |
| Beta-blockers | 34 (47.2) |
| Amiodarone | 39 (54.2) |
| ACE inhibitors/ABRs | 57 (79.2) |
| Furosemide | 18 (25.0) |
| Statins | 21 (29.2) |
| Aspirin | 30 (41.7) |
| Oral anticoagulant | 2 (2.8) |
| Spironolactone | 19 (26.4) |
| Electrocardiographic features | |
| First degree ABV | 22 (30.6) |
| Right bundle branch block | 41 (56.9) |
| Left anterior superior hemiblock | 47 (65.3) |
| QRS < 120 ms | 24 (33.3) |
| QRS > 120 ms | 48 (66.7) |
| Normal QRS-T angle | 39 (54.2) |
| Abnormal QRS-T angle | 21 (29.2) |
| Borderline QRS-T angle | 10 (13.9) |
| Echocardiographic characteristics | |
| Ejection fraction (mean) | 49.8 ± 16.1% |
| Diastolic dysfunction | 42 (58.3) |
| Systolic dysfunction | 3 (4.2) |
| Intracardiac thrombus | 1 (1.4) |
| Left ventricular aneurysm | 3 (4.2) |
| Holter findings | |
| 0-10 ventricular extrasystoles / hour | 12 (16.7) |
| 11-30 ventricular extrasystoles / hour | 10 (13.9) |
| > 31 ventricular extrasystoles / hour | 43 (59.7) |
| Nonsustained ventricular tachycardia | 37 (51.4) |
TIA: transitory ischemic attack; ACE: angiotensin-converting enzyme; ABRs: angiotensin II receptor blockers; ABV: atrioventricular block.