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. 2015 Jan 1;25(1):85–94. doi: 10.1089/thy.2014.0155

FIG. 6.

FIG. 6.

Transmembrane protease serine 4 (TMPRSS4) expression correlates with cyclic adenosine monophosphate response element-binding protein (CREB)-cyclin D1 signaling in thyroid primary cancer. (A) Expression of TMPRSS4 is associated with p-CREB and cyclin D1 expression levels in clinical thyroid cancer specimens. Two representative cases are shown. (B) Percentage of specimens showing low or high TMPRSS4 expression in relation to the expression levels of p-CREB and cyclin D1. (C) The association of TMPRSS4 and cyclin D1 in 358 cases of thyroid cancer specimens using RNAseqV2 data sets deposited on TCGA website. For (B) and (C), *p<0.05.