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. 2014 Dec 16;13:196. doi: 10.1186/1476-511X-13-196

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© Lee et al.; licensee BioMed Central. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Primary points at which PUFA-based supplements enter the PUFA biosynthetic pathway. The biosynthesis of n-6 and n-3 PUFAs proceeds in parallel pathways utilizing the same set of fatty acid desaturase (FADS) and elongase (ELOVL) enzymes. Components of the dietary oils (Table 3) enter as both n-6 (LA, GLA) and n-3 (ALA, SDA, EPA, DPA, and DHA) PUFAs.