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. 2014 Dec 18;53(1):160–166. doi: 10.1128/JCM.02562-14

TABLE 1.

Susceptibility results and acquired resistance genes identified in 98 sequenced E. coli genomes of the four major STs

ST Yr (n) No. of genomes Resistance toa:
Acquired resistance gene(s)
AMX CIP CTX CAZ CXM GEN IPM TZP
73 2001–2003 (20) 5
2 sul, aadA
1 R
4 R blaTEM-1
1 R blaTEM-1, sul
1 R blaTEM-1, sul, aph(6)-Id
1 R blaTEM-1, dfrA, aadA
1 R I blaTEM-1, sul, dfrA, tet(A), aph(6)-Id, aadA
1 R blaTEM-1,sul, tet(A), aph(6)-Id
1 R blaTEM-1, sul, dfrA, tet(A), aph(6)-Id, aadA
1 R blaSHV-1, sul, tet(D), aadA
1 R R blaSHV-2, tet(D)
2010 (18) 9
1 aadA
1 sul, aadA
1 dfrA, aadA
1 R blaTEM-1
1 R I blaTEM-1
1 R blaTEM-1, sul
1 R blaTEM-1, tet(A)
1 R blaSHV-1, sul, tet(D), aadA
1 R R R blaOXA-1, tet(A), aadA
95 2001 (10) 4
1 dfrA, tet(A)
1 R blaTEM-1
2 R blaTEM-1, sul, dfrA, aph(6)-Id
1 R blaTEM-1, sul, aadA
1 R blaTEM-1, sul, aph(6)-Id
2010 (14) 5
1 sul, dfrA, aph(6)-Id, aadA
1 sul, dfrA, tet(A), aadA
2 R blaTEM-1
1 R R blaTEM-1
1 R blaTEM-1, sul, dfrA, aph(6)-Id
1 R I blaTEM-1
1 R blaTEM-30, sul, dfrA, tet(A), aph(6)-Id, aadA
1 R blaTEM-1,sul, dfrA, tet(A), aadA
69 2001–2003 (5) 1 sul, dfrA, tet(A), aadA
1 R blaTEM-1, sul, dfrA, tet(A), aph(6)-Id, aadA
2 R blaTEM-1, sul, dfrA, tet(A), aph(6)-Id
1 R blaTEM-1, sul, tet(A), aph(6)-Id
2010 (9) 2
1 R blaTEM-1
1 R blaTEM-1, sul, dfrA
2 R blaTEM-1, sul, dfrA, aph(6)-Id, aadA
2 R I blaTEM-1, sul, dfrA, tet(A), aph(6)-Id, aadA
1 R blaTEM-1, sul, dfrA, tet(A), aph(6)-Id, aadA
131 2001–2003 (5) 1
1 R blaTEM-1
1 R blaTEM-1, sul, aph(6)-Id
1 R blaTEM-1, tet(A)
1 R R blaTEM-1, sul, dfrA, aadA
2010 (17) 1 R
1 R sul, dfrA, aadA
1 R R sul, dfrA, aadA, ant(2″)-Ia
2 R blaTEM-1, tet(A)
1 R R blaTEM-1, aac(3)-IId
1 R R blaTEM-1, tet(A)
1 R R R blaTEM-1, sul, dfrA, tet(A), aph(6)-Id, aadA
1 R R I blaOXA-1, tet(A), aac(6)-Ib-cr
1 R R R R blaCTX-M-15, sul, dfrA, aadA
1 R R R R blaCTX-M-15, blaOXA-1, sul, dfrA, aac(6)-Ib-cr, aadA
1 R R R R I blaCTX-M-15, blaOXA-1, sul, dfrA, aac(6)-Ib-cr, aadA
2 R R R I R I blaCTX-M-15, blaOXA-1, sul, dfrA, tet(A), aac(6)-Ib-cr, aadA
1 R R R R R R I blaCTX-M-15, blaOXA-1, sul, dfrA, tet(A), aac(6)-Ib-cr, aadA, aac(3)-IIa
1 R R R R R I blaCTX-M-15, blaOXA-1, blaTEM-1, tet(A), aac(6)-Ib-cr
1 R R R I R I blaCTX-M-15, blaOXA-1, blaTEM-1, sul, dfrA, tet(A), aac(6)-Ib-cr, aadA
a

AMX, amoxicillin; CIP, ciprofloxacin; CTX, cefotaxime; CAZ, ceftazidime; CXM, cefuroxime; GEN, gentamicin; IMP, imipenem; TZP, piperacillin plus 4 mg/liter tazobactam; R, resistant; I, intermediate. The empty cells indicate susceptibility. Susceptibility was defined according to BSAC/EUCAST breakpoints.