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. 2014 Dec 18;53(1):248–254. doi: 10.1128/JCM.02690-14

TABLE 1.

Details of the diagnostic criteria for various clinical presentations of aspergillosis included in the study

Groupa Criteria
Aspergillus disease
    CPA (i) Abnormal radiological/CT scan images
(ii) Alteration of the patient's general state
(iii) Aspergillus sp.-positive culture (±3 mo) from respiratory sample or biopsy specimen and/or Aspergillus fumigatus precipitin IgG
    Aspergilloma (i) Radiological/CT scan Monad's sign
(ii) No deterioration of the patient's general state
(iii) Aspergillus sp.-positive culture (±3 mo) from respiratory sample or biopsy specimen and/or Aspergillus fumigatus precipitin IgG
    ABPAb (i) Degradation of respiratory functions
(ii) Global IgE level of ≥1,000 kIU/liter
(iii) Aspergillus-specific IgE level of ≥0.7 kIU/liter
(iv) Global IgE level of ≥500 kIU/liter
(v) Aspergillus sp.-positive culture (±3 mo) and/or Aspergillus fumigatus precipitin IgG and/or an abnormal radiological status
Colonization
    Aspergillus colonization (i) Two Aspergillus sp.-positive cultures from respiratory samples collected between ≥10 days apart and ≤6 mo apart
(ii) No Aspergillus disease criterion
Control
    Blood donors Randomly selected blood donor sera
a

The Aspergillus disease and Aspergillus colonization groups are included in the aspergillosis sensu lato group. CPA, chronic pulmonary aspergillosis; ABPA, allergic bronchopulmonary aspergillosis; CT, computed tomography.

b

Criteria i, ii, and iii or i, iii, iv, and v are mandatory.