Table 1.
Specific activities of TrxR, GPx, and Cat enzymes in the given period, after incubation of A549 and K562 cells, with IC50 values of metal complexes.
| A549 | K562 | ||||
|---|---|---|---|---|---|
| U/mg protein | U/mg protein | ||||
| TrxR | Control C1 C2 C3 |
0.5080ax ± (0.00458)y
0.4740a ± (0.00529) 0.2600b ± (0.01114) 0.2960b ± (0.00557) |
TrxR | Control C1 C2 C3 |
1.0640a ± (0.00529) 0.5867d ± (0.01155) 0.7200b ± (0.05568) 0.6070c ± (0.02000) |
|
| |||||
| GPx | Control C1 C2 C3 |
0.1520a ± (0.00265) 0.0680c ± (0.00854) 0.1067b ± (0.00351) 0.0460d ± (0.00361) |
GPx | Control C1 C2 C3 |
0.2367a ± (0.00577) 0.0200b ± (0.00000) 0.0000b ± (0.00000) 0.0000b ± (0.00000) |
|
| |||||
| Cat | Control C1 C2 C3 |
854.73a ± (0.00008) 281.68c ± (0.00005) 530.41b ± (0.00002) 252.36d ± (0.00002) |
Cat | Control C1 C2 C3 |
354.9300a ± (3.27432) 131.8900b ± (1.47401) 121.9100c ± (1.80602) 108.8163d ± (2.78970) |
Among groups xmean value (n = 3), ystandard deviation, a–dSignificant differences (1: P ≤ 0.05; 2: P ≤ 0.01; 3: P ≤ 0.001) in a row.