Table II.
Associations between CHIEF pathway and colon and rectal cancer overall and by tumor molecular phenotype
| Sub-Pathway | Colon cancer | Rectal cancer | ||
|---|---|---|---|---|
| Subpathway | Overall pathway | Subpathway | Overall pathway | |
| P value | P value | P value | P value | |
| Angiogenesis | 0.703 | 0.030 | 0.402 | 0.064 |
| Hormone/insulin/growth | 0.077 | 0.790 | ||
| Interferon | 0.025 | 0.379 | ||
| Interleukin | 0.123 | 0.024 | ||
| Jak/Stat/Socs | 0.011 | 0.471 | ||
| Pathway core | 0.183 | 0.165 | ||
| MAPK | 0.164 | 0.368 | ||
| Selenoprotein | 0.856 | 0.0047 | ||
| Telomere | 0.040 | 0.122 | ||
| TGFβ | 0.004 | 0.516 | ||
| TLR | 0.223 | 0.428 | ||
| TNF | 0.151 | 0.204 |
Bold values indicate significant at <0.05 level.