Table III.

Multiple regression analysis of the association between preeclampsia and umbilical cord blood stem/progenitor cell population

Umbilical cord blood cell populations	N	Difference (%)a	95 % CI	P value
Initial total nucleated cells	216	−16.32	−27.7 to −3.14	0.017
Initial total mononuclear cells	216	−10.39	−23.35 to 4.77	0.17
Hematopoietic stem cells
CD34+	216	−12.10	−42.42 to 34.19	0.55
CD34+CD38−	218	13.78	−22.37 to 66.77	0.51
Endothelial progenitor cells
CD34+CD133+	118	−52.51	−75.91 to −6.39	0.032
CD34+ VEGFR2+	118	−11.27	−58.47 to 89.59	0.76
CD133+VEGFR2+	118	−33.91	−74.04 to 68.21	0.38
CD34+CD133+VEGFR2+	118	−54.51	−83.84 to 28.08	0.13
Breast stem cells
EpCAM+	167	−41.48	−64.71 to −2.94	0.038
EpCAM+CD49f+	163	−51.93	−71.60 to −18.65	0.007
EpCAM+CD49f+CD117+	88	−22.97	−67.75 to 83.99	0.55
CD49f+CD24+	106	−12.49	−57.01 to 78.15	0.71
CD24+CD29+	108	13.99	−43.68 to 130.70	0.71
CD49f+CD24+CD29+	104	−12.65	−60.80 to 94.60	0.74

CI, confidence interval. The analysis controlled for clinical variables include mother’s age, parents’ ethnicity (both Caucasian versus other), number of previous live births, gestation durations, gender of baby, time at delivery (day or night) and birth weight. The analysis included samples with no missing data on the covariates.

^aProportional difference in stem cell numbers comparing PE with non-PE samples.