Table IV.

Multiple regression analysis of the association between preeclampsia and umbilical cord blood stem/progenitor cell population according to newborn gender

Umbilical cord blood cell populations	Female				Male
	N	Difference (%)a	95 % CI	P value	N	Difference (%)a	95 % CI	P value
Initial total nucleated cells	106	6.67	−15.06 to 33.96	0.58	110	−26.23	−39.00 to 10.77	0.002
Initial total mononuclear cells	106	8.04	−15.21 to 37.67	0.53	110	−18.42	−33.67 to 0.34	0.054
Hematopoietic stem cells
CD34+	105	−14.31	−55.50 to 65.00	0.64	111	−10.53	−49.48 to 58.45	0.70
CD34+CD38−	107	13.40	−38.59 to 109.39	0.69	111	15.25	−30.40 to 90.84	0.58
Endothelial progenitor cells
CD34+CD133+	56	−18.44	−75.02 to 166.24	0.73	62	−62.86	−85.06 to −7.67	0.034
CD34+ VEGFR2+	56	68.05	−58.45 to 579.70	0.46	62	−25.27	−71.00 to 92.62	0.54
CD133+VEGFR2+	56	108.84	−56.73 to 907.83	0.35	62	−60.37	−89.16 to 44.95	0.16
CD34+CD133+VEGFR2+	56	−19.53	−86.14 to 367.33	0.81	62	−64.17	−91.56 to 52.14	0.16
Breast stem cells
EpCAM+	83	−55.77	−79.99 to 2.23	0.044	84	−32.34	−66.74 to 37.65	0.28
EpCAM+CD49f+	80	−64.92	−85.17 to 17.06	0.018	83	−41.14	−71.42 to 21.24	0.15
EpCAM+CD49f+CD117+	43	−12.53	−80.57 to 293.70	0.86	45	−37.07	−80.02 to 98.25	0.42
CD49f+CD24+	52	14.33	−69.81 to 333.04	0.84	54	6.01	−51.17 to 130.14	0.88
CD24+CD29+	54	−19.46	−76.77 to 179.25	0.73	54	58.09	−36.70 to 294.80	0.32
CD49f+CD24+CD29+	51	−18.21	−83.69 to 310.19	0.80	53	2.07	−59.16 to 155.10	0.96

CI, confidence interval. The analysis controlled for clinical variables include mother’s age, parents’ ethnicity (both Caucasian versus other), number of previous live births, gestation durations, time at delivery (day or night), and birth weight. The analysis included samples with no missing data on the covariates.

^aProportional difference in stem cell numbers comparing PE with non-PE samples.