Figure 4.
PTPN22 KO increases autoantibody production in female BXSB mice. A) Sera from PTPN2 KO (squares) and WT (circles) BXSB female mice were collected and anti-chromatin antibody levels were measured by ELISA (WT n=8, KO n=8). Part A also includes male BXSB.Yaa as a comparison (triangles). B) shows proteinuria concentration in PTPN22 KO and WT mice (WT n=8, KO n=7). * p<0.05.