Table.
Subject Clinical History, MGD Grade, and Immunohistochemistry Findings
| Patient Age, y | Surgical Indication | Rosacea | MGD Grade
|
Ki67 LI | Cytoplasmic PPAR γ a | CD45 Infiltrationb
|
||
|---|---|---|---|---|---|---|---|---|
| Expression | Dropout | Acini | Duct | |||||
| 18 | Orbit tumor | − | 0 | 0 | 37.2 | ++ | − | NA |
| 44 | Cicatricial ectropion | − | 1 | 1 | 21.9 | ++ | − | NA |
| 58 | Basal cell cancer | + | 1 | 1 | 13.3 | + | + | + |
| 60 | NA | NA | NA | NA | 19.4 | + | − | − |
| 65 | Trichiasis | + | 3 | 3 | 8.0 | − | − | + |
| 66 | Involutional ectropion | − | 1 | 1 | 8.2 | + | − | NA |
| 67 | Involutional ectropion | + | 2 | 2 | 20.8 | + | − | NA |
| 68 | Involutional ectropion | + | 3 | 2 | 8.3 | + | ++ | + |
| 68 | Involutional ectropion | + | 3 | 3 | 8.0 | NA | − | − |
| 69 | Involutional ectropion | − | 1 | 1 | 8.8 | + | − | NA |
| 71 | Blepharoplasty | + | 2 | 1 | 19.9 | − | − | − |
| 72 | Involutional ectropion | − | 2 | 2 | 10.0 | + | − | NA |
| 72 | Involutional ectropion | + | 2 | 1 | 12.3 | + | − | NA |
| 72 | Eyelid retraction | − | 3 | 3 | 13.6 | + | + | NA |
| 73 | Trichiasis | − | 2 | 2 | 5.1 | − | + | + |
| 74 | Involutional ectropion | NA | NA | NA | 8.9 | NA | + | NA |
| 74 | Thyroid ophthalmopathy | + | 2 | 2 | 8.0 | − | − | − |
| 74 | Involutional ectropion | + | 4 | 4 | 7.0 | + | + | NA |
| 79 | Involutional ectropion | + | 4 | 4 | 6.5 | + | ++ | + |
| 80 | Involutional ectropion | + | 3 | 3 | 14.3 | + | − | − |
| 81 | Dermatochalazis | + | 3 | 2 | 3.4 | − | + | − |
| 81 | Involutional ectropion | + | 3 | 3 | 0.0 | − | + | + |
| 81 | Involutional ectropion | − | 3 | 3 | 7.4 | − | + | NA |
| 82 | Involutional ectropion | + | 2 | 2 | 11.2 | + | − | NA |
| 82 | Involutional ectropion | + | 3 | 2 | 8.2 | + | + | + |
| 83 | Involutional ectropion | − | 3 | 1 | 14.4 | NA | − | NA |
| 84 | Involutional ectropion | + | 4 | 4 | 11.1 | − | − | + |
| 85 | Involutional ectropion | + | 3 | 3 | 11.0 | + | + | NA |
| 85 | Involutional ectropion | + | 3 | 3 | 16.3 | − | ++ | + |
| 85 | Involutional ectropion | + | 3 | 3 | 8.1 | − | + | + |
| 87 | Benign eyelid lesion | + | 4 | 4 | 7.0 | − | − | NA |
| 88 | Involutional ectropion | − | 4 | 4 | 13.7 | + | NA | NA |
| 89 | Involutional ectropion | + | 3 | 3 | 12.0 | + | ++ | + |
| 92 | Involutional ectropion | + | 4 | 3 | 2.5 | − | ++ | NA |
| 93 | Involutional ectropion | + | 3 | 2 | 18.4 | − | + | − |
| 95 | Involutional ectropion | + | 3 | 3 | 16.5 | − | − | + |
Abbreviation: LI, labeling index; MGD, meibomian gland dysfunction; NA, not available; PPAR γ, peroxisome proliferator–activated receptor.
a
++ Indicates staining in all acinar cells; +, staining in basal cells; −, no staining.
b
− Indicates no infiltration; +, fewer than 5 cells; ++, more than 5 cells acini or duct staining with CD45.