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NRG1-ERBB4 neuroimaging epistasis. a. Impact of NRG1 rs10503929 by ERBB4 rs1026882 epistatic effect on DLPFC neural processing. b. Extracted parameter estimates from the DLPFC peak where individuals who were homozygous for the risk SNPs in both NRG1 and ERBB4 were disproportionately inefficient in cortical processing. c. Individuals who carried all 3 NRG1- ERBB4-AKT1 risk genotypes appeared disproportionately inefficient in DLPFC function at this same DLFPC location.
