Table 3.
Multivariate Analysis Thyroid Cancer-Specific Mortality (Age Comparison with Cutoff of 45 Years)
| Covariate | HR | p value | 95% confidence interval | |
|---|---|---|---|---|
| Age at diagnosis | ||||
| Age <45 | reference | |||
| Age >45 | 19.2 | <0.001 | 13.8 | 26.8 |
| Sex | ||||
| Male | reference | |||
| Female | 0.7 | 0.001 | 0.6 | 0.9 |
| Race | ||||
| White | reference | |||
| Black | 1.0 | 0.807 | 0.7 | 1.5 |
| Asian | 0.8 | 0.427 | 0.4 | 1.4 |
| Hispanic | 1.0 | 0.716 | 0.8 | 1.2 |
| Other | 0.9 | 0.246 | 0.7 | 1.1 |
| T stage | ||||
| 1a | 0.2 | <0.001 | 0.1 | 0.3 |
| 1b | 0.3 | <0.001 | 0.2 | 0.4 |
| 2 | reference | |||
| 3 | 2.6 | <0.001 | 1.9 | 3.5 |
| 4 | 3.3 | <0.001 | 2.7 | 4.0 |
| N stage | ||||
| 0 | reference | |||
| 1a | 2.6 | <0.001 | 1.9 | 3.5 |
| 1b | 3.3 | <0.001 | 2.7 | 4.0 |
| M stage | ||||
| M0 | reference | |||
| M1 | 13.1 | <0.001 | 10.7 | 16.1 |
| RAI | ||||
| RAI use | reference | |||
| No RAI | 1.3 | 0.002 | 1.1 | 1.5 |
| Decade of diagnosis | ||||
| 1973–1979 | reference | |||
| 1980–1989 | 2.9 | <0.001 | 2.0 | 4.2 |
| 1990–1999 | 1.6 | <0.001 | 1.3 | 1.9 |
| 2000–2009 | omitted | |||
Reference groups are: RAI, age <45, male, white, T2, N0, M0. Number of observations: 61,049. Bold indicates statistical significance.
RAI, radioactive iodine.