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. 2015 Jan 12;10(1):e0116236. doi: 10.1371/journal.pone.0116236

Table 3. Susceptibility Interpretation of Broth Microdilution Test.

NTM species M. abscessus M. massiliense
Antibiotics Day 3 Day 5 Day 3 Day 5
MIC*range %SI MIC90# MIC range %SI MIC90 MIC range %SI MIC90 MIC range %SI MIC90
Amikacin (AMK) 8 to 16 100 16 8 to 16 100 16 8 to >32 90.9 32 8 to >32 90.9 32
Ciprofloxacin (CPF) 4 to 32 0 32 8 to >32 0 >32 1 to >32 27.3 8 4 to >32 0 32
Levofloxacin (LVF) 16 to 32 0 32 32 to >32 0 >32 8 to 32 0 32 16 to >32 0 >32
Moxifloxacin (MXF) 4 to 16 0 16 8 to 32 0 32 1 to 16 9.1 16 4 to >32 0 32
Gatifloxacin (GAF) 1 to 16 30.7 8 8 to 32 0 32 1 to 16 18.2 8 16 to 32 0 32

Antimicrobial MIC break points (S,I,R): AMK(16,32,64); CPF(1,2,4); LVF(1,2,4); MXF(1,2,4); GAF(1,2,4) (μg/mL) (S, I, R: susceptible, intermediate susceptible and resistant)

*MIC(μg/mL): minimum inhibitory concentration

%SI: percentage of susceptible or intermediate susceptible to antibiotics

#MIC90: MIC required to inhibit the growth of 90% of the organism