Table 4. Extended Screening on Inducible Resistance to Clarithromycin (CLA).
NTM species | Day 3 | Day 5 | Day 14 | |
---|---|---|---|---|
M. abscessus | MIC* range | ≤ 0.06 to 1 | ≤ 0.06 to 4 | ≤ 0.06 to > 32 |
MIC90 # | 0.5 | 4 | > 32 | |
%R※ | 0 | 0 | 69.3 | |
M. massiliense | MIC range | ≤ 0.06 | ≤ 0.06 to 0.125 | ≤ 0.06 to 0.125 |
MIC90 | ≤ 0.06 | 0.125 | 0.125 | |
%R | 0 | 0 | 0 |
CLA break points (S, I, R):(2,4,8) (μg/mL) (S, I, R: susceptible, intermediate susceptible and resistant)
*MIC(μg/mL): minimum inhibitory concentration
※%R: percentage of resistance to antibiotics
#MIC90: MIC required to inhibit the growth of 90% of the organism