. Author manuscript; available in PMC: 2015 Jan 12.

Published in final edited form as: Clin Pract (Lond). 2014;11(5):525–535. doi: 10.2217/cpr.14.46

Table 2.

Formulas used to estimate glomerular filtration rate.

Name of equation	Comments
MDRD study	Less accurate at eGFR >60 ml/min/1.73 m² and older age
CockroftGault	Decreased accuracy at lower levels of CKD
CKD-EPI Scr	Overestimates CKD in older individuals
CKD-EPI cystatin C	Better for older individuals and those with reduced muscle mass
CKD-EPI Cr-cystatin C	Performs better than all above in estimating GFR. Better in elderly
Berlin initiative study (BIS-1)	Reliable for use in the elderly with stage 1–3 CKD, CKD-EPI be used in stages CKD 4–5

CKD: Chronic kidney disease; CKD-EPI: Chronic kidney disease epidemiology collaboration; eGFR: Estimated glomerular filtration rate; MDRD: Modification of diet in renal disease; Scr: Serum creatinine.