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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Neurotoxicol Teratol. 2014 Nov 8;47:54–65. doi: 10.1016/j.ntt.2014.10.007

Fig. 3. Conditioned Fear/Latent Inhibition.

Fig. 3

One male/female pair per litter received fear conditioning with no exposure to the tone prior to tone-shock pairing (NPE) and a second male/female pair per litter received fear conditioning with tone exposure prior to tone-shock pairing (PE). Day-1: training; day-2: test of contextual freezing; day-3 test of cued freezing. Panels: A, day-2, contextual freezing in NPE subgroup; B, day-2 contextual freezing in PE subgroup; C, day-3 freezing prior to tone onset in NPE subgroup; D, day-3 freezing prior to tone onset in PE subgroup; E, day-3 cued freezing after tone onset in NPE subgroup; F, day-3 cued freezing after tone onset in PE subgroup. Data are mean ± SEM. Groups sizes: Total (M/F): Saline = 79 (39/40); Poly IC (H) = 39 (19/20); Poly IC (L) = 40 (20/20) where half of each group of each sex were in the NPE subgroup and half in the PE subgroup. *P<0.05 vs. Saline for the combined NPE-PE Poly IC (L) group males vs. the combined NPE-PE Saline group males.