TABLE 2.
Proportions of Chlamydia trachomatis and Neisseria gonorrhoeae positive screening diagnoses and association with preceding use of antibiotics from a total of 14,775 STI clinic consultations
| Group |
C. trachomatis |
N. gonorrhoeae |
||||
|---|---|---|---|---|---|---|
| % (n) | ORa (95% CI) |
% (n) | OR (95% CI) |
|||
| Univariate | Adjustedb | Univariate | Adjusted | |||
| Women | ||||||
| No antibiotic use (n = 6,320) | 10.6 (667) | 1 | 1 | 1.1 (67) | 1 | 1 |
| Antibiotic use (n = 1,099) | 11.0 (121) | 1.05 (0.85–1.29) | 1.09 (0.89–1.34) | 1.4 (15) | 1.29 (0.73–2.29) | 1.23 (0.70–2.18) |
| Heterosexual men | ||||||
| No antibiotic use (n = 4,579) | 12.1 (556) | 1 | 1 | 1.0 (48) | 1 | 1 |
| Antibiotic use (n = 428) | 8.6 (37) | 0.69 (0.49–0.97)* | 0.76 (0.54–1.08) | 0.9 (4) | 0.93 (0.33–2.59) | 0.83 (0.29–2.33) |
| MSM | ||||||
| No antibiotic use (n = 2,075) | 9.7 (201) | 1 | 1 | 6.4 (132) | 1 | 1 |
| Antibiotic use (n = 274) | 5.5 (15) | 0.54 (0.29–1.00)* | 0.49 (0.26–0.89)* | 6.6 (18) | 1.04 (0.64–1.69) | 0.91 (0.59–1.47) |
a
Risk estimates for the total group are not presented since C. trachomatis estimates significantly differed between women and heterosexual men (P interaction = 0.039) and between women and MSM (P interaction = 0.024). For N. gonorrhoeae the risk estimates did not differ between sexual orientation groups and the overall univariate OR (1.09; 95% CI, 0.77 to 1.54). Analyses accounted for repeated measurements. *, P < 0.05.
b
Adjusted for age and HIV status.