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. 2014 Dec 23;59(1):129–135. doi: 10.1128/AAC.03822-14

TABLE 2.

Activities of PA-824 and TBA-354 in a continuation phase model in experiment 2

Treatment (dose [mg/kg]) Mean ± SD lung log10 CFU on:
Day −42 Day 0 Wk 4 Wk 8 Wk 12
Day 0 to wk 4
    RHZ 2.97 ± 0.02 7.00 ± 0.14 3.58 ± 0.25
Wk 4 to 12
    None 4.94 ± 0.34
    RH 0.80 ± 0.28
    PA-824 (50) 3.19 ± 0.33 2.47 ± 0.06
    TBA-354 (10) 2.65 ± 0.15 2.10 ± 0.08