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Dose-response and kill kinetics of TBA-354 against chronic TB in mice. Eight weeks of treatment at 10 to 100 mg/kg: treatment initiated on day 49 postinfection. Dosages are in mg/kg. All mice were sacrificed prior to treatment or at 2, 4, and 8 weeks posttreatment. Data points are offset in order to minimize overlap. Del, delamanid; TBA, TBA-354.
