Pharmacodynamics of vancomycin (a), piperacillin-tazobactam (b), and ampicillin-sulbactam (c) in the following groups: aerobiosis (gray triangles and lines), aerobiosis plus mucin (red circles and lines), and anaerobiosis plus mucin (black squares and lines). For the aerobiosis group (gray triangles), no antibiotic fit Hill's equation in terms of fAUC/MIC (VAN) or fT>MIC (SAM and TZP) against E. faecium ATCC 19434 or E. faecalis ATCC 29212.