FIG 6.

MEDI4893* enhances neutrophil and macrophage infiltration. Skin lesions from S. aureus SF8300-infected mice treated with VAN, LZD, MEDI4893*, R347, or antibiotic-MEDI4893* combinations were collected at 24, 72, or 168 h postinfection, and the neutrophils and macrophages were enumerated by flow cytometry as described in Materials and Methods. Cell number differences were calculated with Student's t test and considered statistically significant if the P value was <0.05 (*). Results are representative of 2 independent experiments.