FIG 1.

Effects of the addition of R262K to H51Y on integrase strand transfer activity. (A) Relative strand transfer activities with various recombinant protein concentrations. Columns represent the means and standard errors of three independent experiments. (B) Relative strand transfer activities in the presence of various target DNA concentrations. Points represent the means and standard errors of seven independent experiments. (C) K_m values. Columns represent the means and standard errors of seven independent observations. (D) Recombinant enzyme efficiencies, as determined by dividing V_max by K_m. Columns represent the means and standard errors of seven independent experiments.