FIG 5.

Comparative analysis of therapeutic efficacies of PC-SA-SSG versus PC-DDAB-SSG formulations against L. donovani AG83 infections. (A) In vitro leishmanicidal activity was documented as the number of amastigotes in 200 macrophages after 72 h of treatment. Data represent means of three independent experiments performed in triplicate. (B) Suppression of liver and spleen parasite burdens in 3-month-infected and treated BALB/c mice. Data represent means ± standard errors (n = 5) of total parasites per organ. ***, P < 0.001 by Student's t test (A) or P < 0.0001 by ANOVA (B).