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phSGM2 accurately detected susceptibility and resistance to all classes of anti-TB drugs. (A and B) cSML generation in H37Rv cells infected by phSGM2 and exposed to first-line (A) and second-line (B) anti-TB drugs. (C) phSGM2 detected resistance to RIF and EMB in RIFr and EMBr H37Rv variants. (D and E) phSGM2 accurately reported the INH and RIF (D) and STR and KAN (E) susceptibility profiles of clinical isolates 386, 622, 7739, 8330, 8668, and 9016.
