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Summary of incidence of peripheral axonal degeneration seen in control and high-dose groups (20 rats/group; 10 rats/sex/group) at 1, 3, 6, and 9 months (includes a 3-month recovery sacrifice after 6 months of dosing). When observed, the severity of degeneration was minimal to mild (score of 1 or 2) on a 4-point scale.
