FIG 2.

Effects of topical CDV and parenteral VIG treatments (each used alone and in combination) and triple therapy (by adding parenteral CDV) on survival rates (A), primary lesion areas (B), and numbers of satellite lesions (C) during a cutaneous vaccinia virus infection in cyclophosphamide-immunosuppressed SHK-1 hairless mice. Treatment regimens were the same as those described for Fig. 1. Standard error bars are shown in panels B and C. Ten mice were in each treatment group. *, P < 0.05, **, P < 0.01, and ***, P < 0.001 (all compared to placebo).