Table 3.

Most strongly associated SNPs in the meta–analysis of all cohorts

SNP	Chr	Pos	RA	NRA	RAF (min–max)	OR	95 % CI	P value	I 2	N	Gene
rs1401327	2	49900987	A	G	0.113–0.174	1.139	1.084–1.198	2.93E−07	0	35,445	NRXN1
rs11690625	2	49908115	C	A	0.113–0.175	1.139	1.084–1.197	2.95E−07	0	35,482	NRXN1
rs17795388	2	49900356	G	A	0.113-0.174	1.139	1.084–1.198	3.10E−07	0	35,442	NRXN1
rs17795358	2	49897928	A	G	0.113–0.173	1.139	1.083–1.197	3.67E−07	0	35,423	NRXN1
rs925931	2	49913312	C	T	0.010–0.173	1.125	1.071–1.182	2.64E−06	3.3	39,567	NRXN1
rs885560	2	49909442	G	A	0.010–0.175	1.123	1.069–1.179	3.46E−06	5.5	39,566	NRXN1
rs6708111	2	49878453	A	C	0.102–0.168	1.124	1.069–1.182	4.42E−06	0	35,282	NRXN1
rs7581641	2	8543557	T	C	0.012–0.103	1.225	1.123–1.336	4.74E−06	0	41,865	NRXN1
rs6892230	5	65175520	A	G	0.016–0.078	1.236	1.133–1.349	1.87E−06	41.3	37,591	NLN
rs12212674	6	22195053	A	T	0.134–0.621	1.086	1.050–1.123	1.49E−06	0	45,134	LINC00340
rs6901423	6	22194271	G	A	0.134–0.621	1.083	1.048–1.120	3.00E−06	0	45,132	LINC00340
rs1034071	6	22205354	C	T	0.137–0.608	1.081	1.046–1.118	3.73E−06	0	45,330	LINC00340
rs7823467	8	60241288	T	C	0.388–0.713	1.085	1.052–1.120	3.47E−07	22.9	45,273	TOX
rs10086929	8	60252851	A	G	0.430–0.709	1.083	1.049–1.118	7.36E−07	22.3	45,156	TOX
rs6471768	8	60230697	T	A	0.435–0.710	1.082	1.048–1.117	1.07E−06	23.9	45,125	TOX
rs4531042	8	60251242	G	A	0.388–0.737	1.082	1.048–1.118	1.45E−06	32.9	45,277	TOX
rs4738757	8	60218783	A	G	0.388–0.701	1.080	1.046–1.115	1.89E−06	26.9	45,122	TOX
rs12675886	8	60309643	C	T	0.458–0.704	1.079	1.045–1.114	2.50E−06	14.3	45,082	TOX
rs6997378	8	60330443	T	G	0.460–0.705	1.077	1.043–1.111	4.95E−06	17.3	45,085	TOX
rs1944146	11	130195372	A	G	0.524–0.608	1.080	1.046–1.115	2.62E−06	17.3	45,243	LOC100507431
rs7934985	11	130194532	G	A	0.523–0.613	1.080	1.046–1.116	2.66E−06	4.8	45,123	LOC100507431

The table shows all SNPs with P < 5.0E−06