Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Jan 12;212(1):5–14. doi: 10.1084/jem.20141318

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 Yang et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 3. — Anti-HMGB1 mAb administration ameliorates APAP-induced liver injury in mice. (A) Mice received an APAP injection (i.p.) followed by treatment with an anti-HMGB1 antibody or control IgG injection (i.p.; see Materials and methods). Animal survival (percent survival) was assessed. n = 20 mice/group. *, P < 0.05 versus IgG group. (B) Serum levels of liver enzyme (ALT) and cytokines (TNF and IL-6) at 24 h after APAP were measured in mice receiving treatment of anti-HMGB1 antibody or control IgG (see Materials and methods). *, P < 0.05 versus IgG group. n = 10 mice/group. (A and B) Data are presented as means ± SEM.