Table 1.
Organ Weights in Wild-Type and Mmp12−/− Mice
| Genotype | Age (wk) | Subcutaneous Fat (mg) | Perigonadal Fat (mg) | Liver (mg) | Spleen (mg) | Kidney (mg) | Heart (mg) | Gastrocnemius Muscle (mg) |
|---|---|---|---|---|---|---|---|---|
| WT | 2 | 106.2 ± 21.9* | 5.6 ± 1.1 | 216.6 ± 11.2 | 31.2 ± 2.9 | 106.1 ± 9.4 | 56.5 ± 8.9 | 30.5 ± 3.5 |
| Mmp12−/− | 2 | 166.5 ± 25.3† | 8.4 ± 1.0† | 230.0 ± 17.6 | 30.8 ± 2.4 | 108.4 ± 7.3 | 60.7 ± 7.4 | 31.6 ± 2.7 |
| WT | 6 | 249.0 ± 20.3 | 101.8 ± 10.4 | 902.5 ± 21.2 | 66.0 ± 6.7 | 271.1 ± 12.4 | 103.8 ± 5.1 | 62.6 ± 6.5 |
| Mmp12−/− | 6 | 323.3 ± 22.8† | 148.0 ± 16.7† | 974.0 ± 76.9 | 70.8 ± 3.3 | 269.4 ± 14.3 | 113.7 ± 2.6 | 65.8 ± 7.4 |
Definition of abbreviation: WT, wild type.
*
Values are mean ± SEM.
†
P < 0.05 versus age-matched WT mice.
Organs were harvested from wild-type and Mmp12−/− mice and weighed at 2 and 6 wk of age.