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. 2014 Oct 23;6(1):73–78. doi: 10.1021/ml5003376

Table 4. Pharmacokinetic Parameters of 14g.

  3 mg/kg
 30 mg/kg
  plasma kidney liver plasma kidney liver
Cmaxa 3.88 0.21 0.23 29.9 9.1 13.4
Tmax (h) 2 2 2 4 4 8
T1/2 (h) 3.0 4.1 3.9 4.1 4.4 5.2
AUC0–24hb 23.0 11.0 13.0 270 98 170
tissue/plasma ratioc   0.48 0.57   0.36 0.63
a

In units of μg·h/mL or μg·h/g.

b

In units of μg/mL or μg/g.

c

Calculated using AUC.