. 2014 Oct 22;6(1):63–67. doi: 10.1021/ml500300c

Table 3. hERG IC₅₀ and Flt-3 IC₅₀ values of selected compounds.

Comp. No.	hERG IC₅₀, μM^a	Flt-3 IC₅₀, nM^a
1	1.9	ND^b
SGI-1776	<1.0	ND^b
9	>30	157
9a	>30	53
11a	>30	271
11b	>30	125

hERG IC₅₀ was determined by WuXi AppTec using the QPatch^HTX functional hERG assay as described in the experimental section. The Flt-3 IC₅₀ of reference compound staurosporine was less than 1 nM.

Values represent the average of at least two separate experiments, and the standard deviation is less than 10% of the mean.

ND, not determined.

Table 3. hERG IC50 and Flt-3 IC50 values of selected compounds.

Table 3. hERG IC₅₀ and Flt-3 IC₅₀ values of selected compounds.