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. 2014 Nov 26;12(1):46–55. doi: 10.1021/mp500405h

Table 1. Median Potency Values (IC50) for Growth Inhibition of the Indicated Human Cancer Cell Lines by 968 (First Column) or MDC (Second Column) and the Maximum Observed Cell Growth Inhibition Obtained for Either Inhibitor (Third/Fourth Columns).

  IC50 (μM)
max inhibition of growth (%)
cell line 968 MDC 968 (30 μM) MDC (120 μM)
MDA-MB-231 4.2 60 103 83
Mia-PaCa-2 6.7 50 92 97
CAMA1 15 70 76 102
SK-BR-3 5.8 50 109 95
MCF-7 12 52 80 66
U-87 MG 4.2 100 88 52
LN-229 6.4 66 77 93
T98G 3.8 >120 93 17