Table 1.
% lesion | ||
---|---|---|
PPTg | SNc | |
|
||
Sham | 0 ± 3 | 0 ± 20 |
PPTg unilateral | 88 ± 6 (*) | - |
SNc unilateral | - | 50 ± 10 (*) |
PPTg-SNc ipsilateral | 63 ± 15 (*) | 45 ± 10 (*) |
PPTg-SNc contralateral | 66 ± 14 (*) | 66 ± 9 (*) |
The effects of unilateral infusion of 24 nmoles ibotenic acid into the PPTg or 0.6 μmoles MPTP into the rat SNc on the extent of damage to the Neu-N positive neurons of the PPTg or to the TH-positive neurons of the SNc was estimated on a linear scale of 0% (no lesion) to 100% (complete lesion) expressed as the mean ± SEM.
P < 0.05 Newman-Keuls after two-way ANOVA.