Figure 5.

Protein Expression of Claudin-19 during Mouse Kidney Development. Immunohistochemistry was performed on paraffin-embedded sections taken from mouse kidneys at E16.5, P1 and P28 as shown. Claudin-19 is expressed in primitive and mature Loop of Henle tubules as indicated by its overlapping expression with Uromodulin at all stages. Claudin-19 shows broader expression than Claudin-16 and also overlaps with Calbindin-D-28K. A higher magnification of the boxed regions are shown to the right of each image and show regions of overlap with Uromodulin or Calbindin-D-28K. Scale bar = 50 μm.