Figure 6.

Claudin-7, 16, and -19 Co-Localize with Tight Junction Markers. Immunofluorescence was performed on cryosections taken from mouse P1 kidneys using antibodies to Claudin-7, -16, and -19 and co-localization was performed using antibodies to 2 tight junction markers, Occludin (A), and ZO-1 (B). Claudin-7 is expressed apically and basolaterally in ureteric bud tubules and is co-expressed with both ZO-1 and Occludin. Claudin-16 is expressed apically in Loop of Henle tubules and is co-expressed with ZO-1 and Occludin. Claudin-19 is expressed apically in Loop of Henle tubules and is co-expressed with ZO-1 and Occludin. Dotted white lines outline tubule segments. Scale bar = 10 μm.