Figure 2.

Biodistribution of 111In-diDTPA (A) and 111In-DTPA (B) at 1?72 h after injection of the radioactivity in nude mice with s.c. NU-12 tumors. Mice received 100 pmol of G250 × DTIn1 bsAb i.v. and 3 days later 7 pmol of 111In-DTPA or 111In-diDTPA. As a reference a separate set of nude mice with s.c. NU-12 xenografts received the directly labeled antibody 111In-DTPA-G250 (C). This research was originally published in Cancer Research by Boerman et al. (16).