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SPECT/CT imaging of mice bearing colon carcinoma xenografts: posterior projections of mice preinjected with (A) CC49-TCO followed 1 day later by 111In-DOTA-tetrazine (1:25, 42 MBq), (B) CC49 followed 1 day later by 111In-DOTA-tetrazine (1:25, 20 MBq), (C) irrelevant Ab (Rtx-TCO; 100 μg) followed 1 day later by 111In-DOTA-tetrazine (1:25, 50 MBq), (D–F) single transverse slices (2 mm) passing through the tumors in (A–C). This research was originally published in Rossin et al. (60).
