1973 |
Identification of shibirets (dynamin) mutant in Drosophila
|
D. Suzuki and C. Poodry |
1974–1976 |
Zipper mechanism for phagocytosis |
S. Silverstein |
1975–1976 |
Isolation of CCVs, purification of clathrin |
B. Pearse |
1982–1984 |
Phosphomannose, M6PR, and lysosomal targeting |
W. Sly, S. Kornfeld, E. Neufeld, G. Sahagian |
1983–1984 |
Isolation of clathrin adapters/localization to distinct membranes |
J. Keen, B. Pearse, M. Robinson |
1986 |
Isolation of endocytosis mutants (End) in yeast |
H. Riezman |
1986–1987 |
Isolation of vacuolar protein sorting mutants in yeast |
S. Emr, T. Stevens |
1986 |
Endosome fusion in vitro |
J. Gruenberg and K. Howell |
1986 |
EGF and insulin receptor signaling from endosomes |
J. Bergeron and B. Posner |
1986 |
Macropinocytosis induced in stimulated cells |
D. Bar-Sagi and J. Feramisco |
1987 |
Endocytic sorting motifs (FxNPxY, YxxF) |
M. Brown and J. Goldstein, I. Trowbridge, T. McGraw |
1987–1989 |
Cloning of CHC, CLC, AP2 |
T. Kirchhausen, M. Robinson |
1988 |
Isolation of biochemically distinct early and late endosomes |
S. Schmid and I. Mellman |
1989–1991 |
Clathrin-mediated endocytosis reconstituted in vitro |
E. Smythe, G. Warren, S. Schmid |
1990 |
Localization of endosomal Rab5 and Rab7 |
P. Chavrier, R. Parton, M. Zerial |
1991 |
Endosome to trans-Golgi network (TGN) transport reconstituted in vitro |
S. Pfeffer |
1992 |
Rab5 and Rab4 as early endocytic regulators in vivo |
M. Zerial, R. Parton, I. Mellman |
1992–1995 |
Caveolin/VIP21 identified as caveolar coat protein |
R. Anderson, T. Kurzchalia, R. Parton, K. Simons |
1992 |
Vacuolar fusion reconstituted in vitro |
W. Wickner |
1992–1994 |
Trigger mechanism for phagocytosis of bacteria |
S. Falkow, J. Galán, J. Swanson |
1993 |
Actin’s role in endocytosis in yeast |
H. Riezman |
1993 |
Isolation of autophagy mutants (Atg) in yeast |
Y. Ohsumi |
1993 |
PI3 kinase activity (PI3P) and endosome function |
S. Emr |
1993 |
Dynamin’s role in clathrin-mediated endocytosis |
R. Vallee, S. Schmid |
1995 |
Dynamin assembles into rings |
S. Schmid, P. De Camilli |
1996 |
Clathrin-mediated endocytosis requirement for signaling |
S. Schmid |
1996 |
Long distance retrograde transport of signaling endosomes in neurons |
W. Mobley |
1996 |
PI5 phosphatase activity (PI(4,5)P2) and clathrin-mediated endocytosis |
P. De Camilli |
1996 |
Ubiquitin-dependent sorting in endocytosis |
R. Haguenauer-Tsapis; L. Hicke and H. Riezman |
1997 |
AP3 and endosomal/lysosomal sorting |
J. Bonifacino, S. Robinson |
1998 |
FYVE fingers bind to PI3P |
H. Stenmark |
1998 |
LBPA in MVB biogenesis |
T. Kobayashi, R. Parton, J. Gruenberg |
1997–1998 |
Sorting nexins |
G. Gill, S. Emr |
1998 |
Structural basis for Y-based sorting signal recognition |
D. Owen |
1998 |
Retromer coat and endosome to TGN sorting |
S. Emr |
1998 |
β-Propeller structure of clathrin heavy chain terminal domain |
T. Kirchhausen and S. Harrison |
1998 |
Cargo-specific subpopulations of clathrin-coated pits |
M. von Zastrow |
1999 |
Structure of the clathrin coat protein superhelical motifs |
J. Ybe and F. Brodsky |
1999 |
Imaging green fluorescent protein–clathrin in living cells |
J. Keen |
1999 |
Biochemical purification of Rab5 effectors |
S. Christoforidis and M. Zerial |
1999 |
Genetic screen for endocytosis mutants in C. elegans
|
B. Grant |
2000 |
Role of endocytosis in establishing morphogenic gradients |
M. Gonzalez-Gaitan, S.M. Cohen |
2000 |
Identification of GGA coats and lysosomal sorting |
J. Bonifacino, S. Kornfeld, M. Robinson |
2000 |
Identification of endosomal sorting complex required for transport (ESCRT) machinery for multivesicular body (MVB) formation |
S. Emr |
2001 |
Ubiquitin-dependent sorting into MVBs |
R. Piper, S. Emr, H. Pelham |
2002 |
Structure of the AP2 core |
D. Owen |
2003 |
Lipid conjugation of LC3/Atg8 |
Y. Ohsumi |
2003–2004 |
siRNA studies of endocytic components |
S. Robinson, E. Ungewickell, A. Sorkin |
2004 |
BAR domains and membrane curvature generation |
H. McMahon, P. De Camilli |
2004 |
8-Å structure of a complete clathrin coat |
T. Kirchhausen and S. Harrison |
2005 |
Modular design of yeast endocytosis machinery |
D. Drubin and M. Kaksonen |
2005 |
Kinome-wide RNAi analysis of clathrin-mediated endocytosis (CME) and clathrin-independent endocytosis (CIE) |
M. Zerial and L. Pelkmans |
2006–2008 |
Reconstitution of dynamin-mediated membrane fission |
A. Roux, P. De Camilli, S. Schmid, J. Zimmerberg, V. Frolov |
2007 |
Glycosphingolipid-induced endocytosis |
L. Johannes |
2009 |
Reconstitution of Rab- and SNARE-dependent vacuolar and endosome fusion from purified components |
W. Wickner, M. Zerial |
2010 |
Cavins as major caveolae coat components |
R. Parton; B. Nichols |
2010 |
Reconstitution of ESCRT-dependent internal vesicle formation |
T. Wollert and J. Hurley |
2012 |
Reconstitution of CCV formation from minimal components |
E. Ungewickell |