Table 3.
Average values for SCORAD, pruritus index, sIgE, sIL-2Rα, sE-selectin, eosinophilocytes, and basophilocytes before and after 4 months of treatment before with either CsA, 3 mg/kg/day or ECP, 2 J/cm2, on two consecutive days every second week.
| ECP |
CsA |
|||||
|---|---|---|---|---|---|---|
| Before | After | Δ (%) | Before | After | Δ (%) | |
| SCORAD | 69 ± 16(n = 15; range: 50–82) | 37 ± 16(n = 15; range: 11–66) | −46 | 67 ± 11(n = 15; range: 41–82) | 44 ± 16(n = 15; range: 22–83) | −34 |
| Pruritus | 6.5 ± 1.8(n = 15; range: 5–10) | 2.4 ± 1.8(n = 15; range: 0–6) | −63 | 7.3 ± 2.1(n = 15; range: 3–10) | 4.0 ± 2.5(n = 15; range: 1–9) | −45 |
| S-Il-2Rα | 1650 ± 298(n = 12; range: 1209–4383) | 1720 ± 986(n = 12; range: 1031–2984) | 4 | 1756 ± 913(n = 12; range: 1013–4516) | 1473 ± 1029(n = 12; range: 835–4383) | −16 |
| S-E-selectin | 74 ± 23(n = 10; range: 25–101) | 77 ± 35(n = 10; range: 27–132) | 4 | 77 ± 35(n = 10; range: 29–130) | 76 ± 32(n = 10; range: 26–122) | −1 |
| IgE | 6341 ± 6509(n = 11; range; 103–17133) | 5936 ± 6534(n = 11; range; 78–16.783) | −6 | 5742 ± 7605(n = 10; 353–24.459) | 5224 ± 5152(n = 10: 155–14.166) | −9 |
| Basophilic granulocytes | 0.054 ± 0.016(n = 12; range: 0.03–0.09) | 0.056 ± 0.014(n = 12; range: 0.05–0.09) | 4 | 0.06 ± 0.015(n = 11; range: 0.03–0.08) | 0.046 ± 0.022(n = 11; range: 0.00–0.08) | −23 |
| Eosinophilic granulocytes | 0.69 ± 0.39(n = 12; range: 0.03–1.56) | 0.63 ± 0.50(n = 12; range: 0.14–1.9) | −9 | 0.85 ± 0.54(n = 12; range: 0.27–1.77) | 0.54 ± 0.36(n = 12; range: 0.14–1.14) | −36 |
For further details please confer the text in the Section “Results.”