Table 4.
Ref. | Year | n | Therapy | Interferon dose | Duration (mo) | SVR |
Harihara et al[154] | 1994 | 3 | IFN | 3-6 MU biw | NA | NA |
Therret et al[155] | 1994 | 13 | IFN | 3-5 MU tiw | About 4 | NA |
Magnone et al[156] | 1995 | 11 | IFN | 1.5-5.0 MU tiw | 6 | NA |
Rostaing et al[157] | 1995 | 14 | IFN | 3 MU tiw | About 5 | 0% |
Ozgür et al[158] | 1995 | 5 | IFN | 4.5 MU tiw | 6 | NA |
Yasumura et al[159] | 1997 | 6 | IFN | 6 MU tiw | About 7 | 33% |
Durlik et al[160] | 1998 | 11 | IFN | 3 MU tiw | About 6 | 0% |
Hanafusa et al[161] | 1998 | 10 | IFN | 9 MU tiw | 6 | 10% |
Tokumoto et al[162] | 1998 | 6 | IFN | 9 MU tiw | 6 | 50% |
Baid et al[163] | 2003 | 12 | IFN + RBV | 3 MU tiw | Variable | 33% |
Tang et al[164] | 2003 | 4 | IFN + RBV | 3 MU tiw | 12 | 50% |
Shu et al[165] | 2004 | 11 | IFN + RBV | 1 MU tiw | 12 | 27% |
Izopet et al[166] | 1997 | 15 | IFN | 3 MU tiw | About 5 | 0% |
Sharma et al[167] | 2006 | 6 | IFN + RBV | 3 MU tiw | About 12 | 33% |
Pageaux et al[168] | 2009 | 8 | PEG-IFNα2a | 180 μg qw | 6-12 | 50% |
Aljumah et al[169] | 2012 | 19 | PEG-IFN + RBV | 90-180 μg qw | 12 | 42% |
Sanai et al[170] | 2013 | 32 | PEG-IFN + RBV | 135-180 μg qw | 12 | 38% |
IFN: Interferon; MU: Million units; biw: Two times a week; NA: Not available; tiw: Three times a week; PEG-IFN: Pegylated interferon; RBV: Ribavirin; SVR: Sustained virological response rate by intention-to-treat analysis.