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Overexpression of E2F-1 induces in situ MGC-803 tumor cell apoptosis. Apoptosis was assessed by terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeling (TUNEL) and hematoxylin and eosin staining. More apoptotic MGC-803 tumor cells were observed in the LV-GFP-E2F-1 group than in the LV-GFP-NC and phosphate buffered saline (PBS) groups (original magnification, × 400).
