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. 2015 Jan 14;21(2):491–501. doi: 10.3748/wjg.v21.i2.491

Figure 7.

Figure 7

Overexpression of E2F-1 alters protein expression of apoptosis regulators. A: Western blot analysis of c-Myc, S-phase kinase-associated protein 2 (Skp2), Bcl-2, cyclin D1, survivin, Bax and glyceraldehyde-3-phosphate dehydrogenase (GAPDH; internal control) in the MGC-803 tumor tissues. Lanes: 1, LV-GFP-E2F-1 group; 2, LV-GFP-NC group; 3, phosphate-buffered saline (PBS) group; B: Quantification showing downregulation c-Myc, Skp2, Bcl-2, cyclin D1, survivin and upregulation of Bax protein levels (n = 8 animals for each condition). aP < 0.05 using analysis of variance and Student-Newman-Keuls analysis.