TABLE 1.

Binding kinetics of the identified tetravalent peptides^a

Tetravalent peptide	KD (μM), mean ± SE (n = 3)	RUmax (AU), mean ± SE (n = 3 to 4)
NKA-tet	0.28 ± 0.01	2,460 ± 57
IIA-tet	0.51 ± 0.05	3,580 ± 52
KGA-tet	0.21 ± 0.01	1,390 ± 77
KMA-tet	0.43 ± 0.03	2,510 ± 71
KFA-tet	0.55 ± 0.04	3,630 ± 44
FRA-tet	0.63 ± 0.11	3,910 ± 95
PQA-tet	0.57 ± 0.01	2,140 ± 19
YTA-tet	0.34 ± 0.03	2,170 ± 364
VIA-tet	0.40 ± 0.01	2,050 ± 202
AAL-tet	1.00 ± 0.14	2,400 ± 175
AAK-tet	0.35 ± 0.02	2,630 ± 35

^aThe binding kinetics of the identified tetravalent peptides to immobilized 1BH were analyzed using the Biacore system. K_D, dissociation constant; RU_max, maximum resonance unit.