Figure 3.

Report of the studies selected, summary of the clinical trials and the scores obtained in evaluating the methodological quality using the Jadad Scale

Article and reference	Type of study, number of patients	Intervention	Follow-up time	Outcome Odds (CI 95%) and p	Jadad Scale
E423 Banks; Bale; Harding, 1994(17)	Randomized clinical trial N=40	Experimental: Polyurethane Control: Hydrocolloid	6 weeks	EG: 12 complete healings	2
				CG: 10 complete healings
				Odds
				1.50[0.42-5.24]
				p=0.525
E346 Day et al., 1995(18)	Randomized clinical trial N=103	Experimental: Triangular hydrocolloid dressing Control: Oval hydrocolloid	-	EG: 17 complete healings	2
				CG: 11 complete healings
				p=0.017
				Odds
				1.96[0.80, 4.80]
E348 Hondé; Derks; Tudor, 1995(19)	Randomized clinical trial N=168	Experimental: Amino acid copolymer membrane Control: Hydrocolloid	8 weeks	EG: 31 complete healings	2
				CG: 23 complete healings
				Odds
				1.79[0.93, 3.44]
				p=0.089
E312 Bale et al.,1997(20)	Randomized clinical trial N= 60	Experimental: Polyurethane foam Control: Hydrocolloid	4 weeks	EG: 7 complete healings	2
				CG: 5 complete healings
				Odds
				1.65 [0.46, 5.95]
				p=0.44
E314 Thomas et al, 1997(21)	Randomized clinical trial N= 99	Experimental: Hydrocolloid Control: Hydropolymer	6 weeks	EG: 16 complete healings	2
				GC: 10 complete healings
				Odds
				1.94[0.78, 4.84]
				p=0.0763
E284 Seeley; Jensen; Hutcherson, 1999(22)	Randomized clinical trial N= 40	Experimental: Hydrocellular Control: Hydrocolloid	8 weeks	EG: 8 complete healings	2
				CG: 8 complete healings
				Odds
				0.92[0.26, 3.29]
				p=0.89
E554 Burgos et al., 2000(23)	Randomized clinical trial N= 37	Experimental: Collagenase Ointment Control: Hydrocolloid	12 weeks	EG: 3 complete healings	1
				CG: 3 complete healings
				Odds
				1.07[0.19, 6.13]
				p=0.451
E627 Graumlich et al., 2003(24)	Randomized clinical trial N= 65	Experimental: Topical collagen Control: Hydrocolloid	8 weeks	EG: 18 complete healings	2
				CG: 15 complete healings
				Odds
				1.06[0.40, 2.81]
				p=0.893
E169 Hollisaz; Khedmat; Yari, 2004(25)	Randomized clinical trial N= 83	Experimental: Hydrocolloid Controls: (1) Phenytoin and (2) simple dressing (gauze)	8 weeks	EG: 23 complete healings	2
				CG 1: 12 complete healings (CI=10.85-57.52) p<0.01
				CG 2: 8 complete healings (CI=25.45-69.61) p<0.005