Table I.
Characteristics | Total cases, n | NF-κB-p65 expression
|
CXCR4 expression
|
||||
---|---|---|---|---|---|---|---|
Low (n=32) | High (n=48) | P-value | Low (n=23) | High (n=57) | P-value | ||
Age, years | |||||||
<5 | 31 | 15 | 16 | 0.249 | 8 | 23 | 0.800 |
≥5 | 49 | 17 | 32 | 15 | 34 | ||
Gender | |||||||
Male | 48 | 17 | 31 | 0.356 | 11 | 37 | 0.209 |
Female | 32 | 15 | 17 | 12 | 20 | ||
Tumor size, cm | |||||||
<3 | 41 | 23 | 28 | 0.244 | 10 | 31 | 0.461 |
≥3 | 39 | 9 | 20 | 13 | 26 | ||
INSS stages | |||||||
I, IIa, IVs | 21 | 13 | 8 | 0.021a | 12 | 9 | 0.0016a |
IIb, III, IV | 59 | 19 | 40 | 11 | 48 | ||
Metastasis | |||||||
Absence | 18 | 12 | 6 | 0.013a | 11 | 7 | 0.002a |
Presence | 62 | 20 | 42 | 12 | 50 |
P<0.05. NF-κB, nuclear factor-κB; CXCR4, CXC chemokine receptor-4; INSS, International Neuroblastoma Staging System.