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. 2014 Dec 10;35(2):349–357. doi: 10.3892/ijmm.2014.2032

Table I.

NF-κB-p65 and CXCR4 expression in neuroblastoma and their association with the clinicopathological characteristics.

Characteristics Total cases, n NF-κB-p65 expression
CXCR4 expression
Low (n=32) High (n=48) P-value Low (n=23) High (n=57) P-value
Age, years
 <5 31 15 16 0.249 8 23 0.800
 ≥5 49 17 32 15 34
Gender
 Male 48 17 31 0.356 11 37 0.209
 Female 32 15 17 12 20
Tumor size, cm
 <3 41 23 28 0.244 10 31 0.461
 ≥3 39 9 20 13 26
INSS stages
 I, IIa, IVs 21 13 8 0.021a 12 9 0.0016a
 IIb, III, IV 59 19 40 11 48
Metastasis
 Absence 18 12 6 0.013a 11 7 0.002a
 Presence 62 20 42 12 50
a

P<0.05. NF-κB, nuclear factor-κB; CXCR4, CXC chemokine receptor-4; INSS, International Neuroblastoma Staging System.