Table 5.

Enriched ingenuity pathway analysis (IPA) categories including differentially expressed genes in the depressed group.

IPA network top 5	Genes	IPA score
DNA replication, recombination, and repair, cellular assembly and organization, cell cycle	ARID4A (p = 0.037); ATRX (p = 0.049); EIF5B (p = 0.021); JMJD1C (p = 0.034); KIF23 (p = 0.028); KIF18A (p = 0.039); LRP2 (p = 0.039); NAP1L1 (p = 0.044); NCKAP1 (p = 0.043); PDE3B (p = 0.040); RAD23A (p = 0.013); SMC2 (p = 0.034); SMC4 (p = 0.024); SMC5 (p = 0.011); SMC6 (p = 0.026); TTK (p = 0.049)	27
Cell cycle, cancer, connective tissue disorders	CHD1 (p = 0.026); CHD9 (p = 0.026); DNAJC10 (p = 0.028); FZD6 (p = 0.018); HOMER1 (p = 0.048); N4BP2L2 (p = 0.029); NIPBL (p = 0.046); PTBP2 (p = 0.041); SKIV2L2 (p = 0.041); SNAPC1 (p = 0.046), YEATS4 (p = 0.026); ZNF638 (p = 0.035)	18
Cellular movement, hematological system development and function, immune cell T rafficking	CENPE (p = 0.026); COPS2 (p = 0.008); LUC7L3 (p = 0.026); MPP6 (p = 0.034); OTUD6B (p = 0.046); PIBF1 (p = 0.044); ROCK1 (p = 0.023); SENP6 (p = 0.021); SENP7 (p = 0.023); STXBP3 (p = 0.026); ZNF146 (p = 0.028)	16
Cardiovascular system development and function, organismal development, visual system development and function	APOC1 (p = 0.034); CHRM3 (p = 0.021); DEK (p = 0.039); DNM1L (0.048); ERBB2IP (0.025); PGF (p = 0.013); PPP1R12A (p = 0.021); RALGPS2 (p = 0.028); RIF1 (p = 0.039); ROCK2 (p = 0.021)	14
Molecular transport, RNA trafficking, connective tissue disorders	DGKH (p = 0.026); FNBP1L (p = 0.046); KTN1 (p = 0.021); NKTR (p = 0.046); RNF19A (p = 0.048); THOC2 (p = 0.028)	9